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Arbutin is a skin whitening agent which is very popular in Japan and Asia countries for skin de-pigmentation, Arbutin inhabits the formation of melanin pigment by inhabiting tyrosinase activity, Arbutin protect the skin against damage caused by free radicals. The combination with Kojic Acid can inhabits Catecholase activity of tyrosinase. Melanocytes treated with Kojic Acid become nondendritic with a decreased melanin content.
